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Clinical Study
The use of infrared laser therapy (LLLT) in the treatment of VENOUS ULCERATION

M.E. Sugrue, FRCSI, J. Carolan, BSc, E.J. Leen, MB, T.M. Feeley, FRCSI, D.J. Moore, FRCSI, G.D. Shanik, FRCSI, Dublin Ireland.

Management of intractable venous ulceration remains an unrewarding task, which is increasingly delegated to the realm of the vascular surgeon. The purpose of this pilot study was to assess the ulcer-healing effects of the newest form of biostimilation—the low power laser (LLLT). Twelve patients with chronic venous ulcers unresponsive to conservative measures were treated with infrared laser irradiation for twelve weeks. Two ulcers healed completely and there was a 27% (p<0.01) reduction in size of the remaining ulcers. Treatment resulted in a 44% (p<0.01) increase in ulcer floor area occupied by healthy granulation tissue. The most dramatic effect of laser treatment was the reduction in ulcer pain, from 7.5 to 3.5 (linear analogue scale) (p<0.001). Laser irradiation had no effect on TcPO2, number of skin capillaries of pericapillary fibrin deposition in the lipodermatosclerotic area around the ulcer. The results of this pilot study are encouraging and a carefully controlled randomized study is indicated to compare low power laser irradiation to conventional treatment in the management of venous ulcers.


(Ann Vasc Surg 1990;4:179-181).
Clinical Studies
  1. Thermographic study of Low Level Laser Therapy for ACUTE-PHASE INJURY

  2. Low-level laser therapy is an important tool to treat disorders of the maxllofacial region (TMJ).

  3. General Motors Study Low Level Laser Therapy in the Treatment of CARPAL TUNNEL SYNDROME

  4. Laser therapy is effective for DEGENERATIVE OSTEOARTHRITIS

  5. Efficacy of low power laser therapy and exercise on pain and functions in CHRONIC LOW BACK PAIN.

  6. Efficacy of low power laser therapy in FIBROMYALGIA: a single-blind, placebo-controlled trial.

  7. Laser Therapy in the Treatment of DENTAL HYPERSENSITIVITY. A Histologic Study And Clinical Application.

  8. Low level laser therapy with trigger points technique: a clinical study of 243 patients. (HEADACHES & faacial pain, skeletomuscular ailments, myogenic NECK PAIN, SHOULDER AND ARM PAIN, epicondylitis humery, tensosynovitis, low back & radicular pain & archilles tendinitis)

  9. Efficacy of low level laser therapy in MYOFASCIAL PAIN SYNDROME: an algometric and thermographic evaluation.

  10. Low-level laser therapy in OSTEOARTICULAR DISEASES in geriatric patients.

  11. WOUND HEALING of animal and human body sport and traffic accident injuries using low-level laser therapy treatment: a randomized clinical study of seventy-four patients with control group.

  12. The interauricular laser therapy of RHEUMATOID ARTHRITIS.

  13. Laser therapy of RHEUMATOID ARTHRITIS

  14. The prevention of INFLAMMATORY COMPLICATIONS IN MANDIBULAR FRACTURES by using infrared laser and magnetic-laser radiation

  15. Laser therapy for FIBROMYOSITIC RHEUMATISMS

  16. The clinical efficacy of low-power laser therapy on pain and function in CERVICAL OSTEOARTHRITIS

  17. Effect of NASA light-emitting diode irradiation on WOUND HEALING

  18. CARPAL TUNNEL SYNDROME pain treated with low-level laser and microamperes transcutaneous electric nerve stimulation: A controlled study

  19. CARPAL TUNNEL SYNDROME: clinical outcome after low-level laser acupuncture, microamps transcutaneous electrical nerve stimulation, and other alternative therapies--an open protocol study

  20. PROMOTION OF ANGIOGENESIS by low energy laser irradiation.

  21. Effect of red and near-infrared laser light on ADENOSINE TRIPHOSPHATE (ATP) in the luciferine–luciferase reaction.

  22. Effect of a diode laser on WOUND HEALING by using diabetic and nondiabetic mice.

  23. Low Level Laser Therapy—a conservative approach to the BURN SCAR

  24. Effects of low-intensity laser therapy on the ORTHODONTIC movement velocity of human teeth: a preliminary study.

  25. Diode Laser In CERVICAL MYOFASCIAL Pain: A Double-Blind Study Versus Placebo

  26. Infared Diode Laser In Low Reactive-Level Laser Therapy (LLLT) For KNEE OSTEOARTHROSIS

  27. Successful Management Of Female Office Workers With "REPETITIVE STRESS INJURY" Or "CARPAL TUNNEL SYNDROME" By A New Treatment Modality Application Of Low Level Laser

  28. The use of infrared laser therapy (LLLT) in the treatment of VENOUS ULCERATION

  29. Light therapy (LLLT) alters gene expression after ACUTE SPINAL CORD INJURY

  30. Low level laser therapy (LLLT) in ambulatory patients with VENOUS STASIS ULCERS

  31. The use of low energy photon therapy (LEPT) in VENOUS LEG ULCERS: a double blind, placebocontrolled study

  32. The effect of infr-ared laser irradiation (LLLT) on the duration and severity of POSTOPERATIVE PAIN: a double blind trial

  33. Effects of phototherapy (LLLT) on pressure ULCER HEALING in elderly patients after a falling trauma. A prospective, randomized, controlled study.

  34. The use of low intensity laser therapy (LLLT) for the TREATMENT OF OPEN WOUNDS in psychogeriatric patients: a pilot study.

  35. Can low reactive-level laser therapy (LLLT) be used in the treatment of NEUROGENIC FACIAL PAIN? A double-blind, placebo controlled investigation of patients with trigeminal neuralgia

  36. Clinical application of GaAlAs 830nm diode laser (LLLT) in treatment of RHEUMATOID ARTHRITIS